Avengers: Infinity War Biggest Opening Weekend Ever. All I can say is Wow…It was expected to do well, but this is incredible. So far this movie has made $250 million the highest opening weekend ever, beating out Star Wars The Force Awakens in 2015, which opened with $248 million. This movie is when all of the Marvel superhero’s get together to stop a villain. I can’t wait to see it. This could be the biggest movie of all time. A Sequel is already in the works, and should debut in May 2019.